Slow-cycling (dormant) cancer cells in therapy resistance, cancer relapse and metastasis
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چکیده
منابع مشابه
Slow-cycling therapy-resistant cancer cells.
Tumor recurrence after chemotherapy is a major cause of patient morbidity and mortality. Recurrences are thought to be secondary to small subsets of cancer cells that are better able to survive traditional forms of chemotherapy and thus drive tumor regrowth. The ability to isolate and better characterize these therapy-resistant cells is critical for the future development of targeted therapies ...
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Tumor recurrence after chemotherapy is a major cause of patient morbidity and mortality. Recurrences are thought to be due to small subsets of stem-like cancer cells that are able to survive chemotherapy and drive tumor re-growth. A more complete understanding of stem-like cancer cell regulation is required to develop therapies to better target and eliminate these cells. Slow-cycling stem cells...
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ژورنال
عنوان ژورنال: Seminars in Cancer Biology
سال: 2021
ISSN: 1044-579X
DOI: 10.1016/j.semcancer.2021.04.021